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PLoS One 10, e0129937, (2015)

Potent therapeutic activity of irinotecan (CPT-11) and its schedule dependency in medulloblastoma xenografts in nude mice

This doesn't necessarily indicate risk, but it does mean we're relying on individual safety profiles and clinical judgment

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Additionally, as an antioxidant, intraperitoneally injected rosmarinic acid reduces estrogen deficiency- and selenite-induced cataract development by inhibiting oxidative stress (174,175)

Secondary antibodies used were donkey anti-goat IgG coupled to Alexa Fluor 488, goat anti-mouse IgG-AF568, goat anti-rabbit IgG-AF568 and/or goat anti-rat IgG-AF555 (all from Life Technologies, 1:1000)